SkinCeuticals A.G.E. Defying Gift Set (Pre Order Shipping October 2026)

SkinCeuticals A.G.E. Defying Gift

A curated anti-ageing gift set pairing two of SkinCeuticals' most advanced glycation-targeting formulas. This bundle brings together the A.G.E. Interrupter Advanced corrective cream and the AGE Interrupter Ultra Serum in a 15ml size, creating a complete treat-and-lift routine for skin showing visible signs of ageing.

Both products are built on over 15 years of SkinCeuticals glycation research and powered by Proxylane, the brand's proprietary biomimetic active. Used together, they work across the dermal and epidermal layers to smooth wrinkles, firm the skin and restore a visibly more youthful complexion.

What is included:

• SkinCeuticals A.G.E. Interrupter Advanced 48ml
• SkinCeuticals AGE Interrupter Ultra Serum 15ml

What the bundle targets:

• Deep wrinkles and fine lines across five facial zones including forehead, nasolabial folds, marionette lines, glabellar lines and crow's feet
• Loss of firmness and facial contour definition
• Glycation-induced skin ageing
• Sagging and skin laxity
• Dull, sallow skin tone linked to A.G.E. accumulation
• Dryness and barrier compromise

About the products:

A.G.E. Interrupter Advanced 48ml

A breakthrough corrective cream formulated with 18% concentrated Proxylane, 4.25% wild fruit flavonoid blend and 0.1% glycyrrhetinic acid. Clinically proven to smooth visible lines and deep wrinkles across five facial zones and deliver 24-hour hydration in a rich, satin texture. Suitable for dry, normal, combination and sensitive skin.

AGE Interrupter Ultra Serum 15ml

An advanced lifting serum formulated with 30% Proxylane, 4.6% wild berry flavonoids, Rhamnose and Gentiana Lutea Root Extract. Works on critical areas of the face including forehead, cheekbones, jaw and neck to deliver a visible lifting effect in just 4 weeks. High tolerance formula suitable for all skin types including sensitive.

Step 1: Serum
Once or twice daily, apply 1 dropper of AGE Interrupter Ultra Serum to the palm of the hand and dab onto forehead, cheeks, chin and neck. Blend into the skin.

Step 2: Cream
Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced onto the entire face, neck and chest.

If using in the morning, apply the serum after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals moisturiser and sunscreen. Apply the cream as the moisturising step.

A.G.E. Interrupter Advanced 48ml

18% Concentrated Proxylane: SkinCeuticals' proprietary biomimetic active ingredient that helps support the skin's structural integrity and correct visible signs of ageing including wrinkles and skin laxity.

4.25% Wild Fruit Flavonoids (Blueberry and Pomegranate Extracts): A dual antioxidant blend that helps defend against glycation, including UV-induced glycation, and protects against free radical damage.

0.1% Glycyrrhetinic Acid: Helps enhance the skin's natural radiance and counter the dull, sallow tone associated with advanced glycation end-product (A.G.E.) accumulation.

3% HEPES: Activates the skin's natural enzymes to promote even cell turnover while maintaining moisture levels.

1% Niacinamide (Vitamin B3): Soothes and helps support the skin's moisture barrier.

Full Ingredients: Aqua/Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii Butter/Shea Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera/Candelilla Wax, Behenyl Alcohol, PEG-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-T-Butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/Capric Triglyceride, Glycyrrhetinic Acid, Parfum/Fragrance, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-DI-T-Butyl Hydroxyhydrocinnamate.

AGE Interrupter Ultra Serum 15ml

30% Proxylane: A high-concentration biomimetic active that stimulates the production of collagen and elastin, improving skin firmness, density and visible lifting in areas prone to sagging.

4.6% Wild Berry Flavonoids: Powerful antioxidants derived from blueberry and pomegranate that fight glycation and protect against free radical damage.

Rhamnose: A plant-derived sugar that promotes cell renewal and improves skin elasticity.

Gentiana Lutea Root Extract: An anti-inflammatory and repairing botanical ingredient that stimulates the production of type I collagen and elastin.

Ectoin: A biotech-produced antioxidant that helps protect skin cells from environmental stress.

Full Ingredients: Aqua/Water/Eau, Propylene Glycol, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Dimethicone, Cetearyl Isononanoate, Isohexadecane, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Diisopropyl Sebacate, VP/VA Copolymer, Hydroxyacetophenone, Phenoxyethanol, Polysilicone-11, Cellulose, Hydrogenated Lecithin, Xanthan Gum, Propanediol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Panthenol, Rhamnose, Ectoin, Cassia Alata Leaf Extract, Maltodextrin, Sorbitol, Vaccinium Myrtillus Fruit Extract, Sodium Hydroxide, Adenosine, Trisodium Ethylenediamine Disuccinate, Punica Granatum Fruit Extract, Gentiana Lutea Root Extract, Hydrolyzed Soy Protein, Sodium Benzoate, Potassium Sorbate, Citric Acid, Parfum/Fragrance.

About SkinCeuticals: SkinCeuticals is a leading cosmeceutical brand founded on the groundbreaking antioxidant research of Dr. Sheldon Pinnell at Duke University. With a science-first philosophy that has driven the brand for over three decades, SkinCeuticals develops high-performance formulas that prevent and correct visible skin damage using clinically proven ingredients.

Endorsed by dermatologists and used in professional skin clinics worldwide, SkinCeuticals is built on three core principles: prevent, correct and protect. Every product in the range is developed with rigorous clinical testing and a commitment to meaningful concentrations of active ingredients, not cosmetic doses.

The A.G.E. Interrupter range represents one of SkinCeuticals' most important areas of research, backed by over 15 years of dedicated study into glycation and its visible effects on skin ageing. Proxylane, the brand's proprietary biomimetic active, is at the heart of this range and is exclusive to SkinCeuticals.

South William Clinic is a trusted authorised partner of SkinCeuticals, bringing you authentic products with the support of our experienced clinical team. We can help you build a personalised SkinCeuticals routine and advise on how to integrate these products with any in-clinic treatments you may be having.

When you choose SkinCeuticals through South William Clinic, you are investing in one of the most rigorously researched skincare brands in the world, recommended by dermatologists and backed by decades of published clinical science.

A.G.E. Interrupter Advanced - Clinical Backing

Backed by over 15 years of SkinCeuticals glycation research. Clinically proven to smooth visible lines and deep wrinkles across five facial zones: forehead wrinkles, nasolabial folds, marionette wrinkles, glabellar wrinkles and crow's feet. Delivers 24-hour hydration.

AGE Interrupter Ultra Serum - Clinical Backing

Visible lifting effect in just 4 weeks. Acts on critical areas of the face including forehead, cheekbones, jaw and neck. High tolerance formula validated for all skin types including sensitive skin.

Q: What is included in the SkinCeuticals A.G.E. Defying Gift?
A: The gift set includes SkinCeuticals A.G.E. Interrupter Advanced 48ml and the AGE Interrupter Ultra Serum 15ml. Together they form a complete anti-ageing routine targeting glycation, deep wrinkles, loss of firmness and skin dullness.

Q: What is glycation and why does it matter for skin ageing?
A: Glycation is a process in which sugar molecules bind to proteins such as collagen and elastin in the skin, forming advanced glycation end-products (A.G.E.s). Over time this causes the skin's structural proteins to become stiff and less functional, leading to wrinkles, loss of firmness and a dull, sallow complexion. Both products in this set are specifically designed to interrupt this process.

Q: What is Proxylane?
A: Proxylane is SkinCeuticals' proprietary biomimetic active ingredient, derived from xylose, a natural plant sugar. It helps support the skin's structural integrity by promoting the components that give skin its firmness, hydration and resilience. The cream contains 18% Proxylane and the serum contains 30%, making this bundle one of the highest-concentration Proxylane routines available.

Q: How do the two products work together?
A: The AGE Interrupter Ultra Serum is applied first and targets the deeper dermal layer, delivering a visible lifting effect across key facial zones including forehead, cheekbones, jaw and neck. The A.G.E. Interrupter Advanced cream is applied second and works at the surface level to smooth fine lines, deliver 24-hour hydration and further interrupt the glycation process. Together they provide a two-layer approach to visible anti-ageing.

Q: Is this suitable for sensitive skin?
A: Yes. Both products are formulated to be well tolerated across all skin types including sensitive skin. The A.G.E. Interrupter Advanced is also suited to dry, normal and combination skin.

Q: Can I buy the products individually as well?
A: Yes. The A.G.E. Interrupter Advanced 48ml and AGE Interrupter Ultra Serum are both available individually on our website.

Q: Is this a good gift for someone new to SkinCeuticals?
A: Yes. This bundle is a strong introduction to SkinCeuticals' anti-ageing range, combining their most clinically backed glycation-targeting products in a format that is easy to use as a two-step routine. It is particularly well suited to anyone in their 40s or older who is looking to address deep wrinkles, firmness and skin dullness.

Q: Do you ship internationally from Ireland and what about customs?
A: Yes, we ship worldwide from our Irish facility. We regularly serve customers in the UK, United States, Germany, Italy, Spain, Cyprus, Australia, France, Netherlands, Canada, and many other countries throughout Europe, Asia, and the Middle East. Please note that customers are responsible for any local customs charges which are outside of our control.