{"product_id":"the-skin-diary-pro-helix-c-collagen-peptide-brightening-serum-30ml","title":"The Skin Diary Pro-Helix C Collagen Peptide Brightening Serum 30ml","description":"\u003ch2\u003eYour morning glow, with firmness in focus\u003c\/h2\u003e\u003cp\u003eThe Skin Diary Pro-Helix C Collagen Peptide Brightening Serum combines vitamin C, antioxidant care and two signalling peptides in one lightweight morning step. Its milky texture absorbs quickly, making room for sunscreen and makeup without a lengthy routine.\u003c\/p\u003e\u003cp\u003eDesigned for skin concerned with dullness, fine lines and lost elasticity, Pro-Helix C pairs visible brightening with care for a firmer, more supple-looking complexion. The neutral-pH, fragrance-free formula is dermatologically approved for sensitive skin, according to the supplied brand information. Individual tolerance can still vary.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSize:\u003c\/strong\u003e 30 mL.\u003c\/p\u003e\u003ch3\u003eWhat makes the formula different?\u003c\/h3\u003e\u003cp\u003eTHDA vitamin C is paired with acetyl-zingerone and two peptides for complementary antioxidant and firmness-focused care. The peptides are described by the brand as targeting collagen-repair signalling and a growth-factor pathway. These mechanisms should not be confused with guaranteed changes in facial volume or a physical lifting effect.\u003c\/p\u003e\u003ch3\u003eThe evidence, explained\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBrightness:\u003c\/strong\u003e 94% showed brighter skin after seven days in an independent clinical study of 35 people, with brightness assessed using a skin gloss meter.[1]\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFine lines and wrinkles:\u003c\/strong\u003e the supplied independent clinical study of 35 people reported a reduction in their visible appearance from seven days.[2]\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElastic-fibre marker:\u003c\/strong\u003e an independent Manchester Patch Test human-skin biopsy assay found a significant increase in fibrillin, a protein in the skin’s elastic-fibre network.[3]\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePerceived firmness:\u003c\/strong\u003e in a separate consumer study of 45 people over 28 days, 87% reported firmer, more plump-looking skin.[3]\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntioxidant signalling:\u003c\/strong\u003e spatial transcriptomic analysis of human skin biopsy reported a 2.4-fold increase in SOD3 gene expression in basal keratinocytes.[4] This is a molecular marker, not a claim of 2.4 times more collagen or sun protection.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThe brand also reports a 32% increase in a collagen-forming gene. The specific gene and supporting study details were not supplied, so this should not be read as a measured 32% increase in skin collagen. Laboratory and biopsy findings are distinct from clinical appearance measurements and consumer feedback. Individual results vary.\u003c\/p\u003e\u003ch3\u003eHow does it compare with L-ascorbic acid?\u003c\/h3\u003e\u003cdiv style=\"overflow-x:auto;max-width:100%;\"\u003e\u003ctable border=\"1\" cellpadding=\"12\" cellspacing=\"0\" style=\"width:100%;border-collapse:collapse;border:1px solid #999;table-layout:auto;\"\u003e\n\u003ccaption\u003eVitamin C approaches: ingredient-led care versus the Pro-Helix C formula\u003c\/caption\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth scope=\"col\" style=\"border:1px solid #999;padding:12px;text-align:left;vertical-align:top;background-color:#f3f3f3;\"\u003eFeature\u003c\/th\u003e\n\u003cth scope=\"col\" style=\"border:1px solid #999;padding:12px;text-align:left;vertical-align:top;background-color:#f3f3f3;\"\u003eL-ascorbic acid-based care\u003c\/th\u003e\n\u003cth scope=\"col\" style=\"border:1px solid #999;padding:12px;text-align:left;vertical-align:top;background-color:#f3f3f3;\"\u003ePro-Helix C\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"border:1px solid #999;padding:12px;text-align:left;vertical-align:top;\"\u003eVisible brightness\u003c\/th\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eUsed for brightening; results depend on formulation.\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003e94% showed brighter skin at seven days in the supplied 35-person study.[1]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"border:1px solid #999;padding:12px;text-align:left;vertical-align:top;\"\u003eCollagen-focused care\u003c\/th\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eVitamin C is used in collagen-supporting skincare.\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eVitamin C plus two signalling peptides; molecular findings are not a direct measurement of collagen gain.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"border:1px solid #999;padding:12px;text-align:left;vertical-align:top;\"\u003eAntioxidant care\u003c\/th\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eProvides antioxidant activity; performance depends on formulation.\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eVitamin C and acetyl-zingerone; a 2.4-fold SOD3 gene-expression finding was reported in biopsy analysis.[4]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"border:1px solid #999;padding:12px;text-align:left;vertical-align:top;\"\u003eElastic-fibre evidence\u003c\/th\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eNo head-to-head elastic-fibre evidence supplied.\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eSignificant fibrillin increase reported in the supplied human-skin biopsy assay.[3]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"border:1px solid #999;padding:12px;text-align:left;vertical-align:top;\"\u003eSensitive-skin formulation\u003c\/th\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003epH, added fragrance and tolerability vary by product.\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eNeutral pH, no added fragrance and dermatological approval for sensitive skin, as described by the brand.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"border:1px solid #999;padding:12px;text-align:left;vertical-align:top;\"\u003eAdded signalling peptides\u003c\/th\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eDepends on the complete formula, not vitamin C alone.\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #999;padding:12px;vertical-align:top;\"\u003eContains two peptides described as targeting collagen-repair and growth-factor signalling.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\u003cp\u003eThis is a formulation comparison, not a direct comparative clinical trial. It does not establish that all L-ascorbic acid serums lack peptides, are unsuitable for sensitive skin or perform less well.\u003c\/p\u003e\u003ch3\u003eHow to use\u003c\/h3\u003e\u003cp\u003eApply evenly over the whole face every morning before sunscreen. The fast-absorbing milky texture is designed to layer with sunscreen and makeup.\u003c\/p\u003e\u003ch3\u003eStudy notes\u003c\/h3\u003e\u003cp\u003e[1] Independent clinical study of 35 people, assessed by skin gloss meter at days 7, 28 and 56; the 94% figure relates to day 7.\u003cbr\u003e[2] Independent clinical study of 35 people with assessments at days 7, 28 and 56.\u003cbr\u003e[3] Independent Manchester Patch Test human-skin biopsy assay for fibrillin. Separate independent consumer study: 45 people, 28 days.\u003cbr\u003e[4] SOD3 gene expression in basal keratinocytes, assessed by spatial transcriptomic analysis of human skin biopsy.\u003c\/p\u003e\u003ch3\u003eIngredient information\u003c\/h3\u003e\u003cp\u003eThe ingredients described here are highlights, not a full ingredient list. Refer to packaging for complete formulation details.\u003c\/p\u003e","brand":"The Skin Diary","offers":[{"title":"Default Title","offer_id":64006672351562,"sku":null,"price":115.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0300\/6785\/files\/RS1023_PRO_HELIX_C_Product.webp?v=1792418031","url":"https:\/\/southwilliamclinic.com\/products\/the-skin-diary-pro-helix-c-collagen-peptide-brightening-serum-30ml","provider":"South William Clinic","version":"1.0","type":"link"}